human ADH5 shRNA silencing Adenovirus

Name 
Ad-h-ADH5-shRNA
Cat No 
shADV-200460
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human ADH5.

shADV-200460
Ad-h-ADH5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ADH-3; ADHX; FALDH; FDH; GSH-FDH; GSNOR; HEL-S-60p
Description (Vector)
ADH5 encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
Gene ID
128
Gene Name (Vector)
alcohol dehydrogenase 5 (class III), chi polypeptide
Gene Symbol
ADH5
HGNC ID
HGNC:253
ORF Size (aa)
1125
ORF Size (bp)
1125 bp
RefSeq ID
NM_000671
RefSeq Synonyms
NM_000671, BC070491, BC014665,
Species
human
UniGene ID
Hs.78989

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.