human COL15A1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human COL15A1.
shAAV-205683
AAV-h-COL15A1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human COL15A1 (collagen type XV alpha 1 chain). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
COL15A1 encodes the alpha chain of type XV collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Type XV collagen has a wide tissue distribution but the strongest expression is localized to basement membrane zones so it may function to adhere basement membranes to underlying connective tissue stroma. Mouse studies have shown that collagen XV deficiency is associated with muscle and microvessel deterioration.
Gene ID
1306
Gene Name (Vector)
collagen type XV alpha 1 chain
Gene Symbol
COL15A1
HGNC ID
HGNC:2192
ORF Size (aa)
4167
ORF Size (bp)
4167 bp
RefSeq ID
NM_001855
RefSeq Synonyms
NM_001855, BC157094,
Species
human
UniGene ID
Hs.409034
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.