human ACP2 shRNA silencing Adenovirus

Name
Ad-h-ACP2-shRNA

Cat No
shADV-200225

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human ACP2.

shADV-200225

Ad-h-ACP2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ACP2 (acid phosphatase 2, lysosomal). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

LAP

Description (Vector)

ACP2 encodes the beta subunit of lysosomal acid phosphatase (LAP). LAP is chemically and genetically distinct from red cell acid phosphatase. The encoded protein belongs to a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Mutations in this gene or in the related alpha subunit gene cause acid phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene ID

Gene Name (Vector)

acid phosphatase 2, lysosomal

Gene Symbol

ACP2

HGNC ID

HGNC:123

ORF Size (aa)

1272

ORF Size (bp)

1272 bp

RefSeq ID

NM_001610

RefSeq Synonyms

NM_001610, NM_001302492, NM_001302491, NM_001302490, NM_001302489, NM_001131064, BC093010, BC003160,

Species

human

UniGene ID

Hs.532492

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.