human ABCB9 shRNA silencing Adenovirus

Name 
Ad-h-ABCB9-shRNA
Cat No 
shADV-200069
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human ABCB9.

shADV-200069
Ad-h-ABCB9-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human ABCB9 (ATP binding cassette subfamily B member 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ABC transporter 9 protein; ATP-binding cassette sub-family B member 9; ATP-binding cassette transporter 9; ATP-binding cassette, sub-family B (MDR/TAP), member 9; EST122234; hABCB9; TAPL; TAP-like protein
Description (eCommerce)
ATP-binding cassette sub-family b member 9 (ABCB9) is also known as Tap-like protein (TAPL). ABCB9 belongs to the ABCD family of peroxisomal half adenosine-triphosphate-binding cassette (ABC) transporters. ABC transporters are categorized into seven subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and white. ABCB9 is a member of the MDR/TAP subfamily and is a multi-pass membrane protein that functions as a peptide transporter involved in processes such as antigen processing.
Description (Vector)
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This family member functions in the translocation of peptides from the cytosol into the lysosomal lumen. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specificities.
Gene ID
23457
Gene Name (eCommerce)
ATP binding cassette subfamily B member 9
Gene Name (Vector)
ATP binding cassette subfamily B member 9
Gene Symbol
ABCB9
HGNC ID
HGNC:50
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2310
ORF Size (bp)
2310 bp
Protein Name (eCommerce)
ATP-binding cassette sub-family B member 9
RefSeq ID
NM_019624
RefSeq Synonyms
NM_203444, NM_019625, NM_019624, NM_001243014, NM_001243013, BC064384, BC017348,
Research Areas
Antigen Processing and Presentation,Immunology,Lysosome,Transport
Research Areas (Faceted)
cell_biology,immunology
Species
human
Target Sentence
ATP-binding cassette sub-family b member 9 (ABCB9) is also known as Tap-like protein (TAPL). ABCB9 belongs to the ABCD family of peroxisomal half adenosine-triphosphate-binding cassette (ABC) transporters. ABC transporters are categorized into seven subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and white. ABCB9 is a member of the MDR/TAP subfamily and is a multi-pass membrane protein that functions as a peptide transporter involved in processes such as antigen processing.
UniGene ID
Hs.511951
UniProt ID (eCommerce)
Q9NP78

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.