human A2ML1 shRNA silencing Adenovirus

Name 
Ad-h-A2ML1-shRNA
Cat No 
shADV-200007
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human A2ML1.

shADV-200007
Ad-h-A2ML1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human A2ML1 (alpha-2-macroglobulin like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CPAMD9
Description (Vector)
A2ML1 encodes a member of the alpha-macroglobulin superfamily. The encoded protein acts as an inhibitor for several proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID: 20805888). Alternative splicing results in multiple transcript variants.
Gene ID
144568
Gene Name (Vector)
alpha-2-macroglobulin like 1
Gene Symbol
A2ML1
HGNC ID
HGNC:23336
ORF Size (aa)
4365
ORF Size (bp)
4365 bp
RefSeq ID
NM_144670
RefSeq Synonyms
NM_144670, NM_001282424, BC172370,
Species
human
UniGene ID
Hs.620532

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.