rat SFRS8 shRNA silencing AAV

Name
AAV-r-SFRS8-shRNA

Cat No
shAAV-294909

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Sfswap.

shAAV-294909

AAV-r-SFRS8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Sfswap (splicing factor SWAP homolog). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Sfrs8; Srsf8

Description (Vector)

Plays a role as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors. Represses the splicing of MAPT/Tau exon 10.

Gene ID

304431

Gene Name (Vector)

splicing factor SWAP homolog

Gene Symbol

Sfswap

ORF Size (aa)

2376

ORF Size (bp)

2376 bp

RefSeq ID

NM_001034924

RefSeq Synonyms

NM_001034924, BC105868,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.