human ITGB2 Over-expression AAV

Name 
AAV-h-ITGB2
Cat No 
AAV-212506
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ITGB2.

AAV-212506
AAV-h-ITGB2

Ready-to-use AAV expressing Human ITGB2 (integrin subunit beta 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7
Description (Vector)
The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.
Gene ID
3689
Gene Name (Vector)
integrin subunit beta 2
Gene Symbol
ITGB2
HGNC ID
HGNC:6155
ORF Size (aa)
2310
ORF Size (bp)
2310 bp
RefSeq ID
NM_000211
RefSeq Synonyms
NM_001303238, NM_001127491, NM_000211, BC005861,
Species
human
UniGene ID
Hs.375957

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.