human ITGB2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ITGB2.
shADV-212506
Ad-h-ITGB2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ITGB2 (integrin subunit beta 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD18; LAD; LCAMB; LFA-1; MAC-1; MF17; MFI7
Description (Vector)
The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.
Gene ID
3689
Gene Name (Vector)
integrin subunit beta 2
Gene Symbol
ITGB2
HGNC ID
HGNC:6155
ORF Size (aa)
2310
ORF Size (bp)
2310 bp
RefSeq ID
NM_000211
RefSeq Synonyms
NM_001303238, NM_001127491, NM_000211, BC005861,
Species
human
UniGene ID
Hs.375957
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.