human ITGB1 Over-expression AAV

Name 
AAV-h-ITGB1
Cat No 
AAV-212500
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ITGB1.

AAV-212500
AAV-h-ITGB1

Ready-to-use AAV expressing Human ITGB1 (integrin subunit beta 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD antigen CD29; CD29; Fibronectin receptor subunit beta; FNRB; glycoprotein IIa; GPIIA; integrin beta 1; integrin beta-1; integrin VLA-4 beta subunit; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); MDF2; MSK12; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLAB; VLA-BETA
Description (eCommerce)
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells [taken from NCBI Entrez Gene (Gene ID: 3688)].
Description (Vector)
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.
Gene ID
3688
Gene Name (eCommerce)
integrin subunit beta 1
Gene Name (Vector)
integrin subunit beta 1
Gene Symbol
ITGB1
HGNC ID
HGNC:6153
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2397
ORF Size (bp)
2397 bp
Protein Name (eCommerce)
Integrin beta-1
RefSeq ID
NM_002211
RefSeq Synonyms
NM_133376, NM_033668, NM_002211, BC020057,
Research Areas
Angiogenesis,Apoptosis,Axon Guidance,Cancer,Cardiac Development,Cardiology,Cardiomyopathy,Cardiovascular,Cell Cycle,Cytoskeleton,EGFR Signaling,HGF Signaling,Host-Virus Interactions,Immunology,Lung Cancer,MAPK Signaling,Neurobiology,Neurodevelopment,PI3K/Akt Signaling,Prolactin Signaling,Rho Signaling,RNA Processing,Signal Transduction,VEGF Signaling
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,cell_cycle,developmental_biology,genetics,transcription_translation,immunology,infectious_disease,neurobiology,signal_transduction
Species
human
Target Sentence
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells [taken from NCBI Entrez Gene (Gene ID: 3688)].
UniGene ID
Hs.643813
UniProt ID (eCommerce)
P05556

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.