rat POLB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Polb.
shAAV-294105
AAV-r-POLB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Polb (DNA polymerase beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
Gene ID
29240
Gene Name (Vector)
DNA polymerase beta
Gene Symbol
Polb
ORF Size (aa)
1008
RefSeq ID
NM_017141
RefSeq Synonyms
NM_017141, BC098668,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.