human POLB shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human POLB.
shAAV-219345
AAV-h-POLB-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human POLB (DNA polymerase beta). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
POLB is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date.
Gene ID
5423
Gene Name (Vector)
DNA polymerase beta
Gene Symbol
POLB
HGNC ID
HGNC:9174
ORF Size (aa)
1008
ORF Size (bp)
1008 bp
RefSeq ID
NM_002690
RefSeq Synonyms
NM_002690, BC106909, BC100288,
Species
human
UniGene ID
Hs.654484
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.