rat PRKRA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Prkra.
shAAV-293947
AAV-r-PRKRA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Prkra (protein activator of interferon induced protein kinase EIF2AK2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RAX
Description (Vector)
Activates EIF2AK2/PKR in the absence of double stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1.
Gene ID
311130
Gene Name (Vector)
protein activator of interferon induced protein kinase EIF2AK2
Gene Symbol
Prkra
ORF Size (aa)
942
ORF Size (bp)
942 bp
RefSeq ID
NM_001024780
RefSeq Synonyms
NM_001024780, BC097446,
Species
rat
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.