human IRF6 Over-expression AAV

Name 
AAV-h-IRF6
Cat No 
AAV-212411
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IRF6.

AAV-212411
AAV-h-IRF6

Ready-to-use AAV expressing Human IRF6 (interferon regulatory factor 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1
Description (Vector)
IRF6 encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.
Gene ID
3664
Gene Name (Vector)
interferon regulatory factor 6
Gene Symbol
IRF6
HGNC ID
HGNC:6121
ORF Size (aa)
1404
ORF Size (bp)
1404 bp
RefSeq ID
NM_006147
RefSeq Synonyms
NM_006147, NM_001206696, BC014852,
Species
human
UniGene ID
Hs.591415

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.