human IQSEC2 Over-expression AAV

Name
AAV-h-IQSEC2

Cat No
AAV-212383

Availability
4-5 weeks

This is an AAV expressing Human IQSEC2.

AAV-212383

AAV-h-IQSEC2

Ready-to-use AAV expressing Human IQSEC2 (IQ motif and Sec7 domain 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BRAG1; MRX1; MRX18; MRX78

Description (Vector)

IQSEC2 encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene ID

23096

Gene Name (Vector)

IQ motif and Sec7 domain 2

Gene Symbol

IQSEC2

HGNC ID

HGNC:29059

ORF Size (aa)

2850

ORF Size (bp)

2850 bp

RefSeq ID

NM_015075

RefSeq Synonyms

NM_015075, NM_001243197, NM_001111125, BC156683,

Species

human

UniGene ID

Hs.496138

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.