rat PSIP1 shRNA silencing AAV

Name
AAV-r-PSIP1-shRNA

Cat No
shAAV-293384

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Psip1.

shAAV-293384

AAV-r-PSIP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Psip1 (PC4 and SFRS1 interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

Ledgf; Psip2; SBP75

Description (Vector)

Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.

Gene ID

313323

Gene Name (Vector)

PC4 and SFRS1 interacting protein 1

Gene Symbol

Psip1

ORF Size (aa)

996

RefSeq ID

NM_175765

RefSeq Synonyms

NM_175765, BC093606,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.