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rat DNASE2A shRNA silencing AAV

Name 
AAV-r-DNASE2A-shRNA
Cat No 
shAAV-293273
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Rat Dnase2.

shAAV-293273
AAV-r-DNASE2A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Dnase2 (deoxyribonuclease 2, lysosomal). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
53
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Dnase2a
Description (Vector)
Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.
Gene ID
171575
Gene Name (Vector)
deoxyribonuclease 2, lysosomal
Gene Symbol
Dnase2
ORF Size (aa)
1053
ORF Size (bp)
1053 bp
RefSeq ID
NM_138539
RefSeq Synonyms
NM_138539, BC091124,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.