human IL2RB Over-expression AAV

Name 
AAV-h-IL2RB
Cat No 
AAV-212175
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IL2RB.

AAV-212175
AAV-h-IL2RB

Ready-to-use AAV expressing Human IL2RB (interleukin 2 receptor subunit beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD122; IL15RB; P70-75
Description (Vector)
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
Gene ID
3560
Gene Name (Vector)
interleukin 2 receptor subunit beta
Gene Symbol
IL2RB
HGNC ID
HGNC:6009
ORF Size (aa)
1656
ORF Size (bp)
1656 bp
RefSeq ID
NM_000878
RefSeq Synonyms
NM_001346223, NM_001346222, NM_000878, BC025691,
Species
human
UniGene ID
Hs.474787

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.