human IL28RA Over-expression AAV

Name 
AAV-h-IL28RA
Cat No 
AAV-212169
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human IFNLR1.

AAV-212169
AAV-h-IL28RA

Ready-to-use AAV expressing Human IFNLR1 (interferon lambda receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CRF2/12; IFNLR; IL-28R1; IL28RA; LICR2
Description (Vector)
IL28RA belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
Gene ID
163702
Gene Name (Vector)
interferon lambda receptor 1
Gene Symbol
IFNLR1
HGNC ID
HGNC:18584
ORF Size (aa)
1563
ORF Size (bp)
1563 bp
RefSeq ID
NM_170743
RefSeq Synonyms
NM_173065, NM_173064, NM_170743, BC140872,
Species
human
UniGene ID
Hs.221375

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.