rat CCR5 shRNA silencing AAV

Name 
AAV-r-CCR5-shRNA
Cat No 
shAAV-291940
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Rat Ccr5.

shAAV-291940
AAV-r-CCR5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Ccr5 (chemokine (C-C motif) receptor 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Ckr5; Cmkbr5
Description (Vector)
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
Gene ID
117029
Gene Name (Vector)
chemokine (C-C motif) receptor 5
Gene Symbol
Ccr5
ORF Size (aa)
1065
ORF Size (bp)
1065 bp
RefSeq ID
NM_053960
RefSeq Synonyms
NM_053960, BC078756,
Species
rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.