rat ACOT8 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Acot8.
shAAV-291932
AAV-r-ACOT8-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Acot8 (acyl-CoA thioesterase 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Pte1
Description (Vector)
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs (By similarity). May be involved in the metabolic regulation of peroxisome proliferation.
Gene ID
170588
Gene Name (Vector)
acyl-CoA thioesterase 8
Gene Symbol
Acot8
ORF Size (aa)
963
ORF Size (bp)
963 bp
RefSeq ID
NM_130756
RefSeq Synonyms
NM_130756, BC078751,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.