rat SCARB1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Rat Scarb1.
shAAV-291420
AAV-r-SCARB1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Rat Scarb1 (scavenger receptor class B, member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Cd36l1; SR-B1; Srb1
Description (Vector)
Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester (By similarity).
Gene ID
25073
Gene Name (Vector)
scavenger receptor class B, member 1
Gene Symbol
Scarb1
ORF Size (aa)
1530
ORF Size (bp)
1530 bp
RefSeq ID
NM_031541
RefSeq Synonyms
NM_031541, BC076504,
Species
rat
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.