rat RGD1304579 shRNA silencing AAV

Name
AAV-r-RGD1304579-shRNA

Cat No
shAAV-291012

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Trim5.

shAAV-291012

AAV-r-RGD1304579-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Trim5 (tripartite motif-containing 5). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

RGD1304579

Description (Vector)

Isoform Alpha is a retrovirus restriction factor, which mediates species-specific, early block to retrovirus infection. Targets retroviral capsid soon after entry into the cell, and prevents reverse transcription of the virus RNA genome. Isoform Alpha trimers may make multiple contacts with the hexameric lattice of CA proteins which constitute the surface of retrovirion core, and somehow inactivate the virus. Restricts efficiently infection by N-MLV, but not HIV-1. May have E3 ubiquitin-protein ligase activity.

Gene ID

308906

Gene Name (Vector)

tripartite motif-containing 5

Gene Symbol

Trim5

ORF Size (aa)

1536

ORF Size (bp)

1536 bp

RefSeq ID

NM_001014023

RefSeq Synonyms

NM_001014023, BC078926,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.