rat HSPBP1 shRNA silencing AAV

Name
AAV-r-HSPBP1-shRNA

Cat No
shAAV-290590

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Rat Hspbp1.

shAAV-290590

AAV-r-HSPBP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Hspbp1 (HSPA (heat shock 70) binding protein, cytoplasmic cochaperone 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.

Gene ID

246146

Gene Name (Vector)

HSPA (heat shock 70) binding protein, cytoplasmic cochaperone 1

Gene Symbol

Hspbp1

ORF Size (aa)

1074

ORF Size (bp)

1074 bp

RefSeq ID

NM_139261

RefSeq Synonyms

NM_139261, BC072541,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.