rat TAF1C shRNA silencing AAV

Name
AAV-r-TAF1C-shRNA

Cat No
shAAV-290410

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Taf1c.

shAAV-290410

AAV-r-TAF1C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Taf1c (TATA-box binding protein associated factor, RNA polymerase 1 subunit C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.

Gene ID

361420

Gene Name (Vector)

TATA-box binding protein associated factor, RNA polymerase 1 subunit C

Gene Symbol

Taf1c

ORF Size (aa)

2529

ORF Size (bp)

2529 bp

RefSeq ID

NM_001014155

RefSeq Synonyms

NM_001014155, BC061804,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.