rat UNC119 shRNA silencing AAV

Name
AAV-r-UNC119-shRNA

Cat No
shAAV-290281

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Rat Unc119.

shAAV-290281

AAV-r-UNC119-shRNA

Ready-to-use AAV expressing shRNA for silencing of Rat Unc119 (unc-119 lipid binding chaperone). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

RRG4; Uncl19

Description (Vector)

Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Binds myristoylated NPHP3; however, in contrast to UNC119B, does not seem to play a major role in ciliary membrane localization of NPHP3. Does not bind all myristoylated proteins. Probably plays a role in trafficking proteins in photoreceptor cells.

Gene ID

29402

Gene Name (Vector)

unc-119 lipid binding chaperone

Gene Symbol

Unc119

ORF Size (aa)

723

RefSeq ID

NM_017188

RefSeq Synonyms

NM_017188, BC062057,

Species

rat

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.