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human ICAM3 Over-expression AAV

Name 
AAV-h-ICAM3
Cat No 
AAV-211749
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ICAM3.

AAV-211749
AAV-h-ICAM3

Ready-to-use AAV expressing Human ICAM3 (intercellular adhesion molecule 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD antigen CD50; CD50; CDW50; ICAM-3; ICAM-R; intercellular adhesion molecule 3
Description (eCommerce)
ICAM-3 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule [taken from NCBI Entrez Gene (Gene ID: 3385)].
Description (Vector)
ICAM3 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule.
Gene ID
3385
Gene Name (eCommerce)
intercellular adhesion molecule 3
Gene Name (Vector)
intercellular adhesion molecule 3
Gene Symbol
ICAM3
HGNC ID
HGNC:5346
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1644
ORF Size (bp)
1644 bp
Protein Name (eCommerce)
Intercellular adhesion molecule 3
RefSeq ID
NM_002162
RefSeq Synonyms
NM_002162, NM_001320608, NM_001320606, NM_001320605, BC058903,
Research Areas
Immunology,Signal Transduction
Research Areas (Faceted)
signal_transduction,immunology
Species
human
Target Sentence
ICAM-3 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule [taken from NCBI Entrez Gene (Gene ID: 3385)].
UniGene ID
Hs.654563
UniProt ID (eCommerce)
P32942

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.