mouse POU5F1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Pou5f1.
shAAV-280990
AAV-m-POU5F1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Pou5f1 (POU domain, class 5, transcription factor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NF-A3; Oct3; Oct-3; Oct3/4; Oct-3/4; Oct4; Oct-4; octamer-binding protein 3; octamer-binding protein 4; octamer-binding transcription factor 3; octamer-binding transcription factor 4 alternative; Otf3; Otf-3; Otf3g; Otf3-rs7; Otf4; Otf-4; POU domain class 5 transcription factor 1 transcript variant 2 oct4b'; POU domain class 5 transcription factor 1 transcript variant 3 oct4b; POU domain, class 5, transcription factor 1
Description (eCommerce)
Oct-4 (Octamer-binding protein 4), also known as Oct 3/4, is a transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Oct-4 forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. It is critical for early embryogenesis and for embryonic stem cell pluripotency [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P20263].
Description (Vector)
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Gene ID
18999
Gene Name (eCommerce)
POU domain, class 5, transcription factor 1
Gene Name (Vector)
POU domain, class 5, transcription factor 1
Gene Symbol
Pou5f1
NCBI Taxonomy ID (eCommerce)
10090.0
ORF Size (aa)
1059
Protein Name (eCommerce)
POU domain, class 5, transcription factor 1
RefSeq ID
NM_013633
RefSeq Synonyms
NM_013633, NM_001252452, BC068268,
Research Areas
Chromatin Remodeling
Research Areas (Faceted)
cell_biology,genetics
Species
mouse
Target Sentence
Oct-4 (Octamer-binding protein 4), also known as Oct 3/4, is a transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Oct-4 forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. It is critical for early embryogenesis and for embryonic stem cell pluripotency [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P20263].
UniGene ID
Mm.17031
UniProt ID (eCommerce)
P20263
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.