mouse PNPLA2 shRNA silencing AAV

Name 
AAV-m-PNPLA2-shRNA
Cat No 
shAAV-280982
Availability
Immediate
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Pnpla2.

shAAV-280982
AAV-m-PNPLA2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Pnpla2 (patatin-like phospholipase domain containing 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
0610039C21Rik; 1110001C14Rik; Atgl; TTS-2.2
Description (Vector)
Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.
Gene ID
66853
Gene Name (Vector)
patatin-like phospholipase domain containing 2
Gene Symbol
Pnpla2
ORF Size (aa)
1461
ORF Size (bp)
1461 bp
RefSeq ID
NM_025802
RefSeq Synonyms
NM_025802, NM_001163689, BC064747, BC044781, BC019188,
Species
mouse
UniGene ID
Mm.29998

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.