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mouse LNPEP shRNA silencing AAV

Name 
AAV-m-LNPEP-shRNA
Cat No 
shAAV-280851
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Lnpep.

shAAV-280851
AAV-m-LNPEP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Lnpep (leucyl/cystinyl aminopeptidase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2010309L07Rik; 4732490P18Rik; CAP; gp160; IRAP; PLAP; vp165
Description (Vector)
Release of an N-terminal amino acid, cleaves before cysteine, leucine as well as other amino acids. Degrades peptide hormones such as oxytocin, vasopressin and angiotensin III, and plays a role in maintaining homeostasis during pregnancy. May be involved in the inactivation of neuronal peptides in the brain. Cleaves Met-enkephalin and dynorphin. Binds angiotensin IV and may be the angiotensin IV receptor in the brain.
Gene ID
240028
Gene Name (Vector)
leucyl/cystinyl aminopeptidase
Gene Symbol
Lnpep
ORF Size (aa)
1788
ORF Size (bp)
1788 bp
RefSeq ID
NM_172827
RefSeq Synonyms
NM_172827, BC120926, BC120925, BC066791,
Species
mouse
UniGene ID
Mm.393452

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.