human HTATSF1 Over-expression AAV

Name 
AAV-h-HTATSF1
Cat No 
AAV-211679
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HTATSF1.

AAV-211679
AAV-h-HTATSF1

Ready-to-use AAV expressing Human HTATSF1 (HIV-1 Tat specific factor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cofactor required for Tat activation of HIV-1 transcription; dJ196E23.2; HIV TAT specific factor 1; HIV Tat-specific factor 1; TATSF1; TAT-SF1
Description (eCommerce)
Tat-SF1 was originally identified as a cellular factor required for the trans-activation of HIV-transcription by the HIV protein, Tat. In the cell, Tat-SF1 functions as a general transcription factor that plays a role in transcriptional elongation.
Description (Vector)
HTATSF1 functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.
Gene ID
27336
Gene Name (eCommerce)
HIV-1 Tat specific factor 1
Gene Name (Vector)
HIV-1 Tat specific factor 1
Gene Symbol
HTATSF1
HGNC ID
HGNC:5276
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2268
ORF Size (bp)
2268 bp
Protein Name (eCommerce)
HIV Tat-specific factor 1
RefSeq ID
NM_014500
RefSeq Synonyms
NM_014500, NM_001163280, BC009896,
Research Areas
Host-Virus Interactions,RNA Binding,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,infectious_disease,transcription_translation
Species
human
Target Sentence
Tat-SF1 was originally identified as a cellular factor required for the trans-activation of HIV-transcription by the HIV protein, Tat. In the cell, Tat-SF1 functions as a general transcription factor that plays a role in transcriptional elongation.
UniGene ID
Hs.204475
UniProt ID (eCommerce)
O43719

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.