human HSPB1 Over-expression AAV

Name 
AAV-h-HSPB1
Cat No 
AAV-211650
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HSPB1.

AAV-211650
AAV-h-HSPB1

Ready-to-use AAV expressing Human HSPB1 (heat shock protein family B (small) member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
28 kDa heat shock protein; CMT2F; epididymis secretory protein Li 102; estrogen-regulated 24 kDa protein; heat shock 27 kDa protein; heat shock 27kD protein 1; heat shock 27kDa protein 1; heat shock protein beta-1; HEL-S-102; HMN2B; HS.76067; HSP 27; Hsp25; HSP27; HSP28; HspB1; SRP27; stress-responsive protein 27
Description (eCommerce)
Heat shock protein 27 (HSP27) is involved in stress resistance and actin organization [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P04792].
Description (Vector)
HSPB1 is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).
Gene ID
3315
Gene Name (eCommerce)
heat shock protein family B (small) member 1
Gene Name (Vector)
heat shock protein family B (small) member 1
Gene Symbol
HSPB1
HGNC ID
HGNC:5246
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
618
Protein Name (eCommerce)
Heat shock protein beta-1
RefSeq ID
NM_001540
RefSeq Synonyms
NM_001540, BC073768, BC012768, BC012292, BC000510,
Research Areas
Angiogenesis,Apoptosis,Breast Cancer,Cancer,Cardiovascular,CD95/FAS Signaling,Cell Cycle,Complexome,Cytoskeleton,Gene Expression,Host-Virus Interactions,Interleukin Signaling,MAPK Signaling,mRNA Binding,Neurobiology,Neurodegeneration,Neurodevelopment,NF-kB Signaling,Proteasome,Protein Folding,Response to Virus,RNA Processing,Signal Transduction,TNF Signaling,Translational Control,VEGF Signaling
Research Areas (Faceted)
cardiovascular,cancer,cell_biology,cell_cycle,developmental_biology,genetics,transcription_translation,immunology,infectious_disease,neurobiology,signal_transduction
Species
human
Target Sentence
Heat shock protein 27 (HSP27) is involved in stress resistance and actin organization [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P04792].
UniGene ID
Hs.520973
UniProt ID (eCommerce)
P04792

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.