human HSH2D Over-expression AAV

Name
AAV-h-HSH2D

Cat No
AAV-211611

Availability
4-5 weeks

This is an AAV expressing Human HSH2D.

AAV-211611

AAV-h-HSH2D

Ready-to-use AAV expressing Human HSH2D (hematopoietic SH2 domain containing). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ALX; HSH2

Description (Vector)

T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 2003 (PubMed 12960172)).(supplied by OMIM, Mar 2008)

Gene ID

84941

Gene Name (Vector)

hematopoietic SH2 domain containing

Gene Symbol

HSH2D

HGNC ID

HGNC:24920

ORF Size (aa)

1059

RefSeq ID

NM_032855

RefSeq Synonyms

NM_032855, NM_001291274, BC025237,

Species

human

UniGene ID

Hs.631617

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.