human HOXD10 Over-expression AAV

Name 
AAV-h-HOXD10
Cat No 
AAV-211471
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HOXD10.

AAV-211471
AAV-h-HOXD10

Ready-to-use AAV expressing Human HOXD10 (homeobox D10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Hox-4.4; HOX4; HOX4D; HOX4E
Description (Vector)
HOXD10 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as 'rocker-bottom foot' deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.
Gene ID
3236
Gene Name (Vector)
homeobox D10
Gene Symbol
HOXD10
HGNC ID
HGNC:5133
ORF Size (aa)
1023
ORF Size (bp)
1023 bp
RefSeq ID
NM_002148
RefSeq Synonyms
NM_002148, BC074760, BC069619,
Species
human
UniGene ID
Hs.123070

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.