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mouse VLDLR shRNA silencing AAV

Name 
AAV-m-VLDLR-shRNA
Cat No 
shAAV-276022
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Vldlr.

shAAV-276022
AAV-m-VLDLR-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Vldlr (very low density lipoprotein receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AA408956; AI451093; AW047288
Description (Vector)
Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).
Gene ID
22359
Gene Name (Vector)
very low density lipoprotein receptor
Gene Symbol
Vldlr
ORF Size (aa)
2538
ORF Size (bp)
2538 bp
RefSeq ID
NM_013703
RefSeq Synonyms
NM_013703, NM_001347441, NM_001161420, BC013622,
Species
mouse
UniGene ID
Mm.393599

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.