human VLDLR shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human VLDLR.
shAAV-227490
AAV-h-VLDLR-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human VLDLR (very low density lipoprotein receptor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CAMRQ1; CARMQ1; CHRMQ1; VLDL-R; VLDLRCH
Description (Vector)
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene.
Gene ID
7436
Gene Name (Vector)
very low density lipoprotein receptor
Gene Symbol
VLDLR
HGNC ID
HGNC:12698
ORF Size (aa)
2622
ORF Size (bp)
2622 bp
RefSeq ID
NM_003383
RefSeq Synonyms
NM_003383, NM_001322226, NM_001322225, NM_001018056, BC144245, BC142653, BC136562,
Species
human
UniGene ID
Hs.370422
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.