human HOXB4 Over-expression AAV

Name 
AAV-h-HOXB4
Cat No 
AAV-211456
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HOXB4.

AAV-211456
AAV-h-HOXB4

Ready-to-use AAV expressing Human HOXB4 (homeobox B4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HOX-2.6; HOX2; HOX2F
Description (Vector)
HOXB4 is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Intracellular or ectopic expression of this protein expands hematopoietic stem and progenitor cells in vivo and in vitro, making it a potential candidate for therapeutic stem cell expansion.
Gene ID
3214
Gene Name (Vector)
homeobox B4
Gene Symbol
HOXB4
HGNC ID
HGNC:5115
ORF Size (aa)
756
ORF Size (bp)
756 bp
RefSeq ID
NM_024015
RefSeq Synonyms
NM_024015, BC049204,
Species
human
UniGene ID
Hs.664706

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.