mouse UBA3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Uba3.
shAAV-275436
AAV-m-UBA3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Uba3 (ubiquitin-like modifier activating enzyme 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
A830034N06Rik; AI256736; AI848246; AW546539; Ube1c
Description (Vector)
Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.
Gene ID
22200
Gene Name (Vector)
ubiquitin-like modifier activating enzyme 3
Gene Symbol
Uba3
ORF Size (aa)
1326
ORF Size (bp)
1326 bp
RefSeq ID
NM_011666
RefSeq Synonyms
NM_011666, NM_001301859, NM_001301858, NM_001301857, NM_001111106, BC002002,
Species
mouse
UniGene ID
Mm.277626
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.