human HNF1A Over-expression AAV

Name 
AAV-h-HNF1A
Cat No 
AAV-211324
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HNF1A.

AAV-211324
AAV-h-HNF1A

Ready-to-use AAV expressing Human HNF1A (HNF1 homeobox A). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
albumin proximal factor; hepatic nuclear factor 1; hepatocyte nuclear factor 1-alpha; HNF1; HNF-1A; HNF-1-alpha; HNF4A; IDDM20; interferon production regulator factor; LFB1; liver-specific transcription factor LF-B1; MODY3; TCF1; TCF-1; Transcription factor 1; transcription factor 1, hepatic; truncated hepatocyte nuclear factor 1 alpha
Description (eCommerce)
Hepatocyte nuclear factor 1-alpha (HNF1-Alpha) is a transcription factor required for the expression of several liver-specific genes. HNF1-Alpha functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in the HNF1A gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas [taken from NCBI Entrez Gene (Gene ID: 6927)].
Description (Vector)
HNF1A is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas.
Gene ID
6927
Gene Name (eCommerce)
HNF1 homeobox A
Gene Name (Vector)
HNF1 homeobox A
Gene Symbol
HNF1A
HGNC ID
HGNC:11621
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1896
ORF Size (bp)
1896 bp
Protein Name (eCommerce)
Hepatocyte nuclear factor 1-alpha
RefSeq ID
NM_000545
RefSeq Synonyms
NM_001306179, NM_000545, BC104910, BC104908,
Research Areas
Chromatin Remodeling,Metabolism/Metabolic Process,Notch Signaling,Signal Transduction,Transcription Factor/Regulator,Wnt Signaling
Research Areas (Faceted)
signal_transduction,cell_biology,transcription_translation,metabolism,signal_transduction,developmental_biology,genetics,transcription_translation,signal_transduction,developmental_biology
Species
human
Target Sentence
Hepatocyte nuclear factor 1-alpha (HNF1-Alpha) is a transcription factor required for the expression of several liver-specific genes. HNF1-Alpha functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in the HNF1A gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas [taken from NCBI Entrez Gene (Gene ID: 6927)].
UniGene ID
Hs.654455
UniProt ID (eCommerce)
P20823

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.