mouse TNFAIP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Tnfaip1.
shAAV-274677
AAV-m-TNFAIP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Tnfaip1 (tumor necrosis factor, alpha-induced protein 1 (endothelial)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Bacurd2; Edp-1; Edp1; Tnfip1
Description (Vector)
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
Gene ID
21927
Gene Name (Vector)
tumor necrosis factor, alpha-induced protein 1 (endothelial)
Gene Symbol
Tnfaip1
ORF Size (aa)
951
RefSeq ID
NM_009395
RefSeq Synonyms
NM_009395, NM_001159392, BC003906,
Species
mouse
UniGene ID
Mm.386774
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.