mouse TNFAIP1 shRNA silencing Adenovirus

Name 
Ad-m-TNFAIP1-shRNA
Cat No 
shADV-274677
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Tnfaip1.

shADV-274677
Ad-m-TNFAIP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Tnfaip1 (tumor necrosis factor, alpha-induced protein 1 (endothelial)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Bacurd2; Edp-1; Edp1; Tnfip1
Description (Vector)
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
Gene ID
21927
Gene Name (Vector)
tumor necrosis factor, alpha-induced protein 1 (endothelial)
Gene Symbol
Tnfaip1
ORF Size (aa)
951
RefSeq ID
NM_009395
RefSeq Synonyms
NM_009395, NM_001159392, BC003906,
Species
mouse
UniGene ID
Mm.386774

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.