human HMGA2 Over-expression AAV

Name 
AAV-h-HMGA2
Cat No 
AAV-211266
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HMGA2.

AAV-211266
AAV-h-HMGA2

Ready-to-use AAV expressing Human HMGA2 (high mobility group AT-hook 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BABL; HMGI-C; HMGIC; LIPO; STQTL9
Description (Vector)
HMGA2 encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene ID
8091
Gene Name (Vector)
high mobility group AT-hook 2
Gene Symbol
HMGA2
HGNC ID
HGNC:5009
ORF Size (aa)
330
RefSeq ID
NM_003483
RefSeq Synonyms
NM_003484, NM_003483, NM_001330190, NM_001300919, NM_001300918, BC160115,
Species
human
UniGene ID
Hs.505924

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.