mouse TESC shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Tesc.
shAAV-274041
AAV-m-TESC-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Tesc (tescalcin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1010001A17Rik; 2410011K10Rik; TE-1
Description (Vector)
Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.
Gene ID
57816
Gene Name (Vector)
tescalcin
Gene Symbol
Tesc
ORF Size (aa)
645
ORF Size (bp)
645 bp
RefSeq ID
NM_021344
RefSeq Synonyms
NM_021344, BC107679, BC019492,
Species
mouse
UniGene ID
Mm.273285
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.