mouse TCFE3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Tfe3.
shAAV-273940
AAV-m-TCFE3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Tfe3 (transcription factor E3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bHLHe33; F830016E06Rik; Tcfe3; Tfe-3
Description (Vector)
Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
Gene ID
209446
Gene Name (Vector)
transcription factor E3
Gene Symbol
Tfe3
ORF Size (aa)
1719
ORF Size (bp)
1719 bp
RefSeq ID
NM_172472
RefSeq Synonyms
NM_172472, NM_001271491, NM_001271490, NM_001271489, NM_001105197, NM_001105196, BC063047, BC056358,
Species
mouse
UniGene ID
Mm.249142
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.