human HJURP Over-expression AAV

Name 
AAV-h-HJURP
Cat No 
AAV-211202
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HJURP.

AAV-211202
AAV-h-HJURP

Ready-to-use AAV expressing Human HJURP (Holliday junction recognition protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
14-3-3-associated AKT substrate; FAKTS; fetal liver expressing gene 1; fetal liver-expressing gene 1 protein; hFLEG1; Holliday junction recognition protein; up-regulated in lung cancer 9; URLC9
Description (eCommerce)
Holliday junction recognition protein (HJURP) is a centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. HJURP acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. HJURP directly binds Holliday junctions [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NCD3].
Gene ID
55355
Gene Name (eCommerce)
Holliday junction recognition protein
Gene Name (Vector)
Holliday junction recognition protein
Gene Symbol
HJURP
HGNC ID
HGNC:25444
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2247
ORF Size (bp)
2247 bp
Protein Name (eCommerce)
Holliday junction recognition protein
RefSeq ID
NM_018410
RefSeq Synonyms
NM_018410, NM_001282963, NM_001282962, BC001940,
Research Areas
Cell Cycle,Cell Division
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
Holliday junction recognition protein (HJURP) is a centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. HJURP acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. HJURP directly binds Holliday junctions [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NCD3].
UniGene ID
Hs.532968
UniProt ID (eCommerce)
Q8NCD3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.