mouse SUMO3 shRNA silencing AAV

Name 
AAV-m-SUMO3-shRNA
Cat No 
shAAV-273466
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Sumo3.

shAAV-273466
AAV-m-SUMO3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Sumo3 (small ubiquitin-like modifier 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2810014B19Rik; D10Ertd345e; SMT3A; Smt3h1; SUMO-3
Description (Vector)
Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4.
Gene ID
20610
Gene Name (Vector)
small ubiquitin-like modifier 3
Gene Symbol
Sumo3
ORF Size (aa)
333
RefSeq ID
NM_019929
RefSeq Synonyms
NM_019929, NM_001301673, NM_001301672, NM_001301671, BC115489, BC115488,
Species
mouse
UniGene ID
Mm.24433

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.