human RB1 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-220819
Availability:
4-5 weeks
Name:
AAV-h-RB1-shRNA
This is an AAV expressing shRNA for silencing of Human RB1.
Request a Quote
Please enter your email address and we'll be in touch with more information:
Product Info
- Knockdown
- >80% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- RB1
- Gene Name
- RB transcriptional corepressor 1
- Gene ID
- 5925
- Gene Synonyms
- OSRC; p105-Rb; pp110; PPP1R130; pRb; RB
- ORF Size
- 2787 bp
- RefSeq#
- NM_000321
- Gene Description
- RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
- UniGene ID
- Hs.408528
- HGNC ID
- HGNC:9884
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
Vector Biolabs
293 Great Valley Parkway
Malvern, PA 19355
Email: info@vectorbiolabs.com
Phone: +1 484-325-5100
Toll-free (US Only): 877-BIO-LABS
Fax: +1 215-525-1112
Privacy Policy