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mouse SORL1 shRNA silencing AAV

Name 
AAV-m-SORL1-shRNA
Cat No 
shAAV-272864
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Sorl1.

shAAV-272864
AAV-m-SORL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Sorl1 (sortilin-related receptor, LDLR class A repeats-containing). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2900010L19Rik; AI596264; AW261561; gp250; LR11; mSorLA; SorLA
Description (Vector)
Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction.
Gene ID
20660
Gene Name (Vector)
sortilin-related receptor, LDLR class A repeats-containing
Gene Symbol
Sorl1
ORF Size (aa)
6648
ORF Size (bp)
6648 bp
RefSeq ID
NM_011436
RefSeq Synonyms
NM_011436, BC172714, BC156440,
Species
mouse
UniGene ID
Mm.121920

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.