mouse SLA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Mouse Sla.
shAAV-272038
AAV-m-SLA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Mouse Sla (src-like adaptor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Slap; Slap-1
Description (Vector)
Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
Gene ID
20491
Gene Name (Vector)
src-like adaptor
Gene Symbol
Sla
ORF Size (aa)
846
ORF Size (bp)
846 bp
RefSeq ID
NM_009192
RefSeq Synonyms
NM_009192, NM_001029841, BC032922,
Species
mouse
UniGene ID
Mm.7601
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.