mouse SLA Over-expression AAV

Name 
AAV-m-SLA
Cat No 
AAV-272038
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Sla.

AAV-272038
AAV-m-SLA

Ready-to-use AAV expressing Mouse Sla (src-like adaptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Slap; Slap-1
Description (Vector)
Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins.
Gene ID
20491
Gene Name (Vector)
src-like adaptor
Gene Symbol
Sla
ORF Size (aa)
846
ORF Size (bp)
846 bp
RefSeq ID
NM_009192
RefSeq Synonyms
NM_009192, NM_001029841, BC032922,
Species
mouse
UniGene ID
Mm.7601

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.