mouse SIRT3 shRNA silencing AAV

Name 
AAV-m-SIRT3-shRNA
Cat No 
shAAV-272009
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Sirt3.

shAAV-272009
AAV-m-SIRT3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Sirt3 (sirtuin 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
2310003L23Rik; AI848213; Sir2l3
Description (Vector)
NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.
Gene ID
64384
Gene Name (Vector)
sirtuin 3
Gene Symbol
Sirt3
ORF Size (aa)
774
RefSeq ID
NM_022433
RefSeq Synonyms
NM_022433, NM_001177804, NM_001127351, BC025878,
Species
mouse
UniGene ID
Mm.244216

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.